Saccharolipids are lipid compounds containing a glycosyl ligand. It is a kind of amphiphilic molecule which exists widely in organism. It is divided into two main categories: glycolyl glycerol and glycosphingolipids. Glycosphingolipids are divided into neutral and acid glycosphingolipids.
Saccharolipids are important components of cell surface antigens. In some normal cells, the surface glycolipid composition changes significantly. Creative Proteomics provides a platform for lipidomics analysis that enables the molecular structure and content analysis of different saccharolipids and other lipids containing fatty acids.
Our Detectable Saccharolipids Include But Are Not Limited To:
- Saccharolipids
| Monogylcosylceramide (CerG1) | Diglycosylceramide (CerG2) | Triglycosyl-ceramide (CerG3) |
| Monogalactosylmonoacylglycerol (MGMG) | Monogalactosyldiacylglycerol (MGDG) | Digalactosylmonoacylglycerol (DGMG) |
| Digalactosyldiacylglycerol (DGDG) | Sulfoquinovosylmonoacylglycerol (SQMG) | Sulfoquinovosyldiacylglycerol (SQDG) |
- Glycoglycerolipids
| Galactolipids | Sulfolipids |
- Glycosphingolipids
| Cerebrosides | Gangliosides | Globosides |
| Glycophosphosphingolipids | Glycophosphatidylinositols |
Our Saccharolipids Analysis Service
Accurate quantification: Use external standard method to quantify, and use internal standard for correction, qualitative and quantitative is more accurate.
High sensitivity: Liquid chromatography coupled with triple quadrupole mass spectrometers for Saccharolipids analysis service (Triple Quad™ 6500 LC-MS/MS System).
Fig 1. The workflow of saccharolipids analysis service.
Sample Preparation
We accept a variety of samples, including but not limited to blood, tissue, cells, etc. If you want to provide other samples, please contact our technicians.
- Serum/plasma and other body fluid samples: ≥ 100ul/sample
- Animal tissues: ≥ 100mg/sample
- Cells/microorganisms: ≥ 107/sample
- Cell supernatant/culture medium supernatant ≥ 2mL
After quick freezing in liquid nitrogen, store at -80°C and send with dry ice.
Why Choose Us?
- One-stop analysis service: Provide comprehensive services from sample preparation, standard addition, mass spectrometry analysis, data processing, and data comparison.
- High sensitivity: High-sensitivity mass spectrometer is used to effectively detect low-level metabolites in the sample.
- High accuracy: The secondary spectra of the collected customer sample substances are matched with the secondary spectra of the self-built standard database one by one intelligently, with high accuracy of substance identification.
- Experienced in sample pre-processing. Can handle various biological fluid and tissue cell samples.
- Professional data analysis: Professional data processing and analysis software, capable of analyzing data by PCA, OPLS-DA, T-test, etc.
- Fast turnaround time: 2-6 weeks.
- Detailed report: Provide a detailed report at the end of the entire project, including the experimental process, MS/MS instrument parameters, quality control parameters, raw data and the final result of the comparison.
If you have any questions about our saccharolipids analysis services, please contact us.